Search results for "Gene expression omnibus"

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Control of dataset bias in combined Affymetrix cohorts of triple negative breast cancer

2014

AbstractHeterogenous subtypes of breast cancer need to be analyzed separately. Pooling of datasets can provide reasonable sample sizes but dataset bias is an important concern. We assembled a combined dataset of 579 Affymetrix microarrays from triple negative breast cancer (TNBC) in Gene Expression Omnibus (GEO) series GSE31519. We developed a method for selecting comparable datasets and to control for the amount of dataset bias of individual probesets.

Poolinglcsh:QH426-470MicroarrayPoolingComputational biologyMicroarrayBiologycomputer.software_genreBiochemistryBreast cancerBreast cancerData in BriefGeneticsmedicineddc:610Affymetrix microarraysTriple-negative breast cancerGene expression omnibusmedicine.diseaselcsh:GeneticsSample size determinationDataset biasMolecular MedicineGene expressionData miningcomputerBiotechnologyGenomics Data
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